Ιωάννινα: Η μυστηριώδης "κυρία από την Αγγλία" και τα e-mails στους ογκολόγους

This workshop will discuss the current state of the art of MRI techniques for measuring neurofluids (dynamics of blood and cerebrospinal fluid (CSF) in the brain), and how the images from these techniques should be interpreted and applied to patients with clinical disorders. Sessions will include a focus on novel methods in phase contrast MRI, functional MRI, ASL, diffusion, and motion-sensitive MRI techniques, and how these techniques can be rigorously validated and accurately interpreted. Sessions will describe the current knowledge about the physiology of CSF flow in the brain at multiple spatial scales, and its links to waste clearance and lymphatic systems. We will discuss many clinical applications of these methods, including in traumatic brain injury, Alzheimer’s disease, sleep and sleep disorders, pediatrics, hydrocephalus, and aging. We will include a practical hands-on session on how to analyze several types of MRI data focused on neurofluid measurement. We will also include a session on open-source data and tools, to enable attendees to begin working with these methods on their own. This workshop provides technical insight, practical knowledge, and clinical context for imaging and understanding CSF and waste clearance systems in the brain.

Host-microbe interactions can be positive or negative for both a host organism and its symbiotic microbes. Interacting with microbes can enable eukaryotes to acquire essential functions, such as metabolite synthesis or the production of defensive chemicals. However, such interactions are often pathogenic in nature.This cross-disciplinary meeting picks up where the well-received first edition in 2023 left off and will bring together scientists using cellular, molecular, ecological, physiological, and theory-based approaches to explore the evolution of intimate species-species interactions. The aim is to understand the cellular systems, metabolic pathways and ecological circumstances that drive transitions in symbiotic states, for example, as partnerships move from pathogenesis to beneficial and back again.One key theme that will be addressed is how hosts distinguish friend from foe. What biological functions- from protein-protein interactions to whole organism behaviours- allow an organism to engage in stable symbiotic interactions. Conversely, which functions ensure partner fidelity and specificity in symbiosis. Such insights will help to understand the complexities of symbiotic function.