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Precisely defining transcription unit boundaries across eukaryotic genomes is fundamental to understanding individual gene function and regulation. The multifaceted process of RNA 3' end formation establishes the functional limits of all transcripts, thereby dictating RNA fates. This area has expanded to encompass several 3’ end formation mechanisms, involving new protein complexes, studied across diverse model systems and scientific disciplines using a range of new techniques. Examples of this complexity include different 3' end formation pathways that determine RNA stability or degradation, and the widespread use of alternative 3' end sites used to modulate RNA function and localisation. These diverse outcomes are regulated during development and stress responses, and their dysregulation is implicated in diseases such as infection and cancer. Continued progress necessitates a synthesised understanding of numerous transcriptional processes and the combined expertise of researchers in transcription, RNA processing, localisation and transport, structural biology, bioinformatics, and technology development. Our Oxford 3' end EMBO Workshop brings together scientists with such expertise to discuss RNA 3' ends and their regulation. This will act as a critical catalyst for further progress and provides an important opportunity for early career scientists to share their work and actively engage with this exciting field.

Modern lipid biology has evolved far beyond the traditional view of lipids as simple building blocks or energy substrates. Lipids are now recognised as dynamic regulators of biological structures and functions. This progress has been driven by remarkable advancements in technologies and experimental tools, which are uncovering new perspectives on lipid functions and their role in organising biological systems. To further advance the field, it is essential to unravel not only the collective properties of lipids but also their structural and functional interactions with proteins in complex biological processes. The EMBO Workshop "Lipid Code to Life" will bring together leading scientists and early-career researchers from diverse disciplines—including lipidomics, chemical biology, structural biology, and membrane biophysics—to discuss the latest discoveries in lipid functions, quality control, and lipid-protein interactions. This EMBO Workshop is designed to create a dynamic and collaborative environment where participants can exchange ideas, build networks, and foster collaborations. By bringing together expertise from a wide range of intersecting fields, our aim is to propel lipid biology forward, driving innovation, new synergies, and growth in this rapidly advancing area of research.

This EMBO Workshop brings together scientists from a broad range of disciplines who are interested in exploring and applying the basic physical principles that underlie the behavior of living cells. This extends from the protein scale up to the tissue level with input from the physical and the biological sciences. We hope to stimulate exchange of ideas between theoreticians and experimentalists, and between physicists, chemists and biologists. Participation of young and emerging scientists is highly encouraged and several slots are reserved for contributed lectures.Topics include:Phase transitionsReconstituted systemsSynthetic CellsBiomolecular condensatesPhysics of chromosomes and the nucleusSensing and InformationMechanics and dynamics of cellsMechanics and dynamics of tissues and organoidsStudents and postdocs not giving a talk are expected to participate through poster presentation.For interested students we also offer a 1-day summer school on the morning and early afternoon of the first day (7th September), introducing the subjects of the conference to solidify the theoretical basis of the themes. To apply, please mark the corresponding field during registration.Please apply early, as this meeting may become oversubscribed before the deadline.