Το ''Καρκινάκι’’ σχεδιάζει το Ψηφιακό Σχολείο του Μέλλοντος για  μικρούς υπερήρωες

Cancer evolution is a multi-faceted process and a major clinical challenge. Indeed, tumors constantly change as they progress through multiple mechanisms, the understanding of which is critical to anticipate disease phenotypes and responses to therapy.This EMBO Workshop will bring together an interdisciplinary community of scientists to facilitate discussion and collaboration on genetic and non-genetic mechanisms of cancer evolution. We will explore a wide spectrum of oncogenic drivers and molecular data types, with a focus on their impact across the three main phases of cancer evolution: initiation, progression, and relapse. This choice was driven by some of the most exciting findings in the last few years exploring, e.g., cancer-associated genetic and non-genetic alterations in normal cells (field cancerization), emerging technologies to monitor tumor progression and response to therapy (e.g., liquid biopsies), and the preponderant role of cell plasticity and lineage reprogramming in therapeutic resistance.Cancer evolution is a multifaceted problem, and as such, a prism of complementary ideas is needed to understand and harness this process.

Funded by EMBO for excellence in the life sciencesThis course will take place at EMBL Grenoble.Course overviewRecent advances in cryo-electron microscopy/tomography (cryo-EM/ET), super-resolution microscopy, and deep-learning-based protein structure prediction, combined with increasingly sophisticated sample preparation methods, have transformed structural biology. Solving the field’s most complex challenges will require researchers who can strategically integrate these powerful tools.This course provides a comprehensive overview of modern structural biology methods, with emphasis on sample preparation, characterisation, and data integration.Key topics include:Multi-subunit protein expression in bacterial, insect, and mammalian systemsIsolation of native complexesIn vitro reconstitution of protein and protein–nucleic acid assembliesBiochemical and biophysical approaches to assess stoichiometry and homogeneityThis latest edition of this long-standing course features a refreshed lineup of speakers and topics, highlighting the strategic use of cutting-edge protein structure prediction methods, and recent advances in in situ structural biology. The programme aims to equip participants with the theoretical and practical skills needed to combine complementary approaches and apply them to contemporary structural biology research.AudienceAdvanced PhD students and postdocs, currently working on challenging projects in structural biology that would benefit form hybrid approaches.Learning outcomesParticipants will learn 3D structure determination of macromolecular assemblies at various resolution scales, and strategies to integrate data from X-ray crystallography, cryo-EM, SAXS, NMR, mass spectrometry, smFRET, and super-resolution microscopy.What past participants say about the course“The course on Structural Characterisation of Macromolecular Complexes was very engaging, with lecturers eager to learn about our projects and providing valuable insights. I also especially appreciated the opportunity to meet fellow students from all over the world.” —Sophie Roth, Harvard University, USA“It was a wonderfully intense experience. I learned more than I thought was possible in a single week.” — Marta Gapinska, University of Warsaw, Poland

There is increasing recognition of the value that strong partnerships between patients, clinicians and researchers can bring to effective delivery of respiratory care. This pre-Congress webinar series introduces the ERS Congress 2026 theme 'United for better breathing: partnership between patients, clinicians and researchers' and explores how co-creation and collaboration can strengthen individual care, improve care delivery, advance meaningful research and amplify the impact of advocacy.The series is co-developed with the European Lung Foundation (ELF), reflecting the joint ERS-ELF commitment to strengthening patient-professional partnership in respiratory care and research. It will explore how co-creation and collaboration can strengthen individual care, improve care delivery, advance meaningful research and amplify the impact of advocacy.Each webinar will feature conversations between healthcare professionals and patients who will use their experience of real world partnerships to highlight both the opportunities and the challenges of working together to support clinical care, co-design services and collaborate on research. The focus is practical, showcasing successful initiatives and offering delegates actionable insights they can apply in their own clinical, research and advocacy activities.Why attend?Hear from patients, clinicians and researchers with practical experience of working together.Reflect on how their hints and tips can support your clinical practice, inform co-design in your clinical services, enhance your research collaborations and add value to your advocacy.Prepare for the ERS Congress 2026 theme, and join a global conversation on working together to improve respiratory health.Learning OutcomesFollowing this webinar series, participants will be aware of the benefits of partnership working for individual patient care, co-design of health care services, research, guideline development, and advocacy. The practical talks from clinicians, patients and researchers will support implementation of partnership working in clinical and research settings to improve care for people with respiratory conditions.Topics and scheduleWriting guidelines together: integrating the patient voice in clinical practice standards27 May, 202617:00-18:00 CESTUsing practical examples from ERS clinical practice guidelines, the clinical, patient and methodological speakers will give their perspectives on how working together strengthens methodology and facilitates implementation of meaningful guidelines in clinical practice.Listening first: identifying and acting on unmet needs1 June, 202617:00-18:00 CESTUsing real-life examples from clinical practice, the clinical and patient speakers will share their experience of co designing accessible and equitable systems in diverse healthcare contexts.Three people together: partnerships involving children, young people and caregivers30 July, 202613:00-14:00 CESTPartnerships with children include at least three people - the child, their parent/carer and the healthcare professional. This webinar will explore the practical strategies that enable the development of effective tripartite partnerships within clinical care, and also the value of engaging with young people as powerful voices in advocacy.Advocacy: making our voices heard21 August, 202614:00-15:00 CESTFrom local Healthy Lungs for Life projects to translating global policy resolutions into national initiatives that enable action, this webinar illustrates the power of speaking together in joint advocacy to influence the policy context and ensure real change that benefits the lung health of populations.Co-creating care: patients as equal partners31 August, 2026, 17:00-18:00 CESTThe partnership between the patient and their clinician underpins clinical care enabling shared decisions about treatment, supported self management, and promotion of healthy lifestyles. Patients and clinicians will discuss their experience of partnerships and the development of trust in working together.Discovering together: advancing science through collaborative research1 September, 2026, 17:00-18:00 CESTPatient involvement throughout the research cycle enhances research. In this webinar, patients and researchers from ERS Clinical Research Collaborations discuss the challenges and successes of their research collaboration in basic, clinical and applied research, with examples from setting research agendas, delivery of research, and dissemination.Check the programme tab for more details regarding each session.FormatSix webinar sessions are planned, with each session running for one hour. The format includes 45 minutes dedicated to talks and activities, concluding with a 15 minute question-and-answer period.Recordings and educational materials will be accessible the day after the webinar and will be freely available as open-access resources.CME creditsAn application will be submitted to the European Board for Accreditation in Pneumology (EBAP) for CME accreditation of this event. The number of credits that you will receive will correspond to the time you spend viewing the sessions live.