Μελέτη αμφισβητεί την αποτελεσματικότητα του καθολικού προσυμπτωματικού ελέγχου για τον καρκίνο του δέρματος στη Γερμανία

The genome carries information across generations, ensuring species survival. To preserve faithful transmission of genetic information, RNA-directed mechanisms safeguard the genome integrity in diverse life forms, from bacteria to mammals. Studies in conventional model organisms and cultured cells have shed light on such mechanisms, but recent discoveries revealed unexpected details of RNA-mediated mechanisms functioning in prokaryotes and non-model organisms. Furthermore, advances in molecular machine structures, spatial gene regulation, and reproductive biology offer crucial insights into RNA-directed genome defense. This EMBO Workshop will connect researchers in transcriptional and post-transcriptional gene regulation, small RNAs, transposons, structural biology, and spatial gene organization to broaden technical expertise and perspectives in the field of RNA-guided genome protection. This EMBO Workshop also aims to strengthen the connection between mechanisms and developmental processes by linking biochemical and biophysical properties of RNA-guided machinery to stem cell maintenance, germ cell development, and reproduction. Lastly, dedicated sessions will explore the history and evolution of RNA-guided mechanisms, from prokaryotic defense to genetic conflict and adaptation.

About this eventLed by ERS President Prof. Joanna Chorostowska-Wynimko, this Summit highlights the successes of early detection in lung cancer screening, the potential of health checks to accelerate detection, and looks to the future at the promise of AI and biotechnology.ProgrammeQuick overview:Session 1: Lung Cancer Screening: a pivotal opportunity for pulmonology EU Cancer PlanSession 2: Health checks – a comprehensive approach to awareness and detectionSession 3: From possibility to reality: delivering on AI’s promiseSession 4: Biotechnology: the future for respiratory diseases?Full programme:View the full programme for this event. Please note that it may be subject to changes.Who should attend?This event will bring together multiple stakeholders from across Europe (both professional and patient) to explore this important topic. We welcome attendance from:Experts in the field of respiratory health and preventionGovernment representativesPublic health representativesHealthcare professionalsPatients/Patient organisation representativesHow do I register?This is a free, in person event. If you are interested in attending and exploring this topic further, please contact alethe.devaulgrenant@ersnet.org to show your interest. Note, there are limited spaces as some attendees will be invited to ensure balanced representation.

Objectives of the CRT meeting on “Decarbonising Cardiology: From Environmental Risk to Cardiovascular Responsibility" This meeting will present health issues associated with harmful environmental behaviours and possible solutions. The goal is to highlight how such behaviours can adversely affect cardiovascular health and overall well-being. The session will conclude with a collaborative discussion aimed at identifying potential recommendations:Identify actionable levers for change across the cardiovascular ecosystemAnalyse regulatory and legislative constraints impacting sustainability efforts.Develop a practical, multi-stakeholder roadmap (including hospitals, patients, and industry) with defined next steps and checkpoints.

Learning objectivesAfter watching this webinar, participants will be able to:critically appraise how age, life expectancy, comorbidity burden, anatomical complexity, and anticipated future treatment needs should inform the timing and selection of the initial valve intervention;compare contemporary surgical and transcatheter valve therapies with regard to durability, haemodynamic performance, device-specific limitations and implications for life-time patient management;integrate predictors of structural valve deterioration, failed repair and reintervention after TAVI and transcatheter mitral/tricuspid procedures into longitudinal Heart Team decision-making; andformulate a patient-centred, life-time management strategy that aligns the index procedure with the feasibility, safety, and anticipated complexity of future reintervention.Needs assessment and expected educational outcomeTo strengthen evidence-based and guideline-informed Heart Team discussions by providing participants with a structured framework for first-intervention strategy, comparative assessment of available valve platforms, and anticipatory planning for future reintervention across the patient life course.Context - Contemporary valvular heart disease management increasingly requires a longitudinal rather than procedure-centred perspective, as expanding transcatheter treatment options, as well as improving survival and broader treatment eligibility have made durability and reintervention planning central components of clinical decision-making.Important educational gaps persist regarding how to balance procedural risk, expected valve longevity, anatomical feasibility, coronary access, valve-in-valve options and the potential need for repeat intervention when choosing between surgical and transcatheter approaches.Main topic:Valvular Heart DiseaseRelated topics:TreatmentInterventionProsthetic Heart ValvesSession informationInterventional cardiologists, cardiac surgeons, cardiovascular imagers, heart valve specialists, heart failure specialists, general cardiologists involved in valve patient pathways, and fellows in training with an interest in structural heart disease and Heart Team decision-making.During the webinar, you will be encouraged to send your questions by chat and interact with our key opinion leaders who will provide live feedback.Technical settingsThe webinar is available on PC and tablets. The use of a smartphone is not recommended.To answer the MCQs during the live, you must allow pop-up windows.A high-speed Internet connection is required (minimum 2 Mbps).An application has been made to the EACCME® for CME accreditation of this event.Additional informationThis webinar is the second part of a connected three-part Structural Heart Disease Implementation Series developed in collaboration with Edwards Lifesciences and aligned with contemporary ESC/EAPCI educational priorities.