Τεχνητός πλακούντας ρίχνει φως στους κινδύνους από τα φάρμακα στην εγκυμοσύνη

This EMBO Workshop explores the gene-regulatory mechanisms that drive developmental reprogramming upon fertilization. It focuses on the interplay of transcriptional, post-transcriptional, and developmental regulation during this universal transition. The meeting will cover exciting advancements in the field, including the discovery of novel mechanisms of translational regulation after fertilization, the identification of new transcription factors mediating genome activation, and the mechanisms of promoter–enhancer activation that initiate transcription. Additionally, it will examine how these regulatory steps shape developmental decisions across species to identify common principles underlying this fundamental transition.This EMBO Workshop will highlight groundbreaking discoveries in developmental reprogramming in vivo and human embryoids, exploring how these systems enhance our understanding of molecular gene regulation and its implications for embryonic development and human fertility. By bringing together researchers interested in this critical transition, the meeting will foster the integration of distinct molecular processes that collectively drive the reprogramming of the nucleus and cytoplasm to initiate embryogenesis. It will showcase the latest genomics and imaging approaches, facilitating cross-disciplinary exchange—from single-molecule imaging to genome architecture, evolutionary insights, and the latest advancements in developmental and cellular reprogramming—ultimately deepening our understanding of how this universal transition shapes gene regulation across species.